ELISIO™-H Dialyzer

ELISIO™ Pynhrn™ Confidence From The Inside Out

When Nipro set out to reimagine the single-use, high-flux, hollow-fiber dialyzer, our goal was to evolve the new ELISIO™ POLYNEPHRON™ into a product delivering multiple, valuable advantages.

Our design and engineering teams
accomplished these objectives,
innovating an array of powerful,
practical features – including
thousands of fibers in each membrane,
with each fiber acting as a nephron.
By utilizing a membrane that functions
more like a human kidney, outstanding
biocompatibility, hemocompatibility, and
solute-removal performance is achieved,
resulting in superior clearances for better
patient outcomes.

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Description

Pynnephron™ State-of-the-Art Membrane

To function more like the human kidney, we built thousands
of fibers into each ELISIO™ dialyzer – thus P™ –
where every fiber acts as a nephron (human kidney element).
This unique hollow-fiber formulation, developed by Nipro,
features a one-of-a-kind, highly optimized structure to
deliver outstanding biocompatibility, hemocompatibility, and
solute-removal performance.

• Newly formulated PES (polyethersulfone) composition
for more well-balanced membrane properties

• 3D chemical structure modeling with ideal mix of hydrophilic
and hydrophobic domains reduces membrane fouling

• Advanced pore-spinning technology creates more
homogenous pore sizes to optimize sieving properties

• Uniform pore size results in improved removal of uremic toxins
and low-molecular-weight proteins, with limited loss
of important proteins such as albumin

• Unique ripple structure inside dialyzer creates less dialysis
channeling for more homogenous flow and better diffusive
transport and enhanced small molecule clearances

 

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